1. Kojic Acid Dipalmitate (Kojic Dipalmitate) Overview
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Kojic Acid Dipalmitate (KAD) is a liposoluble derivative of kojic acid. It’s also called 2- palmitoyl methyl -5- palmitoyl – pyranone. It has a greater ability to inhibit melanin formation than kojic acid. There is no hydroxyl group in its molecular structure, so it won’t form hydrogen bond with other active ingredients in cosmetics to affect their functions, and it has a good compatibility. As a whitening agent, KAD is widely used in cosmetics industry.
Product Name
CAS Number
INCI Name
Kojic Acid Dipalmitate
79725-98-7
Kojic Acid Dipalmitate
Molecular Weight
Molecular Formula
Molecular Structure
C38H66O6
618.93g/mol
Product ID
Specificcation
Minimal Package
Minimal Order Quantity
BFSTAR0801
98%
1KG
1KG
Kojic Acid Vs Kojic Acid Dipalmitate
| Function | Mechanism | Easy to make formula | Stability | Stimulate | Effect | Safety | Price | |
| Kojic Acid | Skin whitening, anti-bacterial | Tyrosinase inhibitor | ++ | ++++ | + | ++++ | ++++ | ++ |
| Kojic Acid Dipalmitate | Skin whitening, moisture | Tyrosinase inhibitor | +++++ | +++++ | – | +++++ | +++++ | +++ |
2. Kojic Dipalmitate Source
Kojic acid is a colorless, odorless, safe and effective tyrosinase inhibitor produced by fermentation. It exists in many brewing foods, including soy sauce, soybean, wine, and so on. The microorganisms that can produce kojic acid are aspergillus parasiticus, aspergillus oryzae , aspergillus flavus, etc. Japan began kojic acid production in the 1970s. Kojic acid is mainly applied in cosmetics and health care products; also it can be used as a natural preservative in the food industry.
3. Kojic Acid Dipalmitate Manufacturer Specifications
| Items | Specifications |
| Assay | Kojic Acid Dipalmitate≥98% |
| Appearance | White sheet crystal powder |
| Melting point | 92-96℃ |
| Loss on Drying | ≤0.5% |
| Residue on ignition | ≤0.5% |
| Color reaction of ferric chloride | Negative |
| Heavy Metal | |
| Total Heavy Metals | ≤10ppm |
| As | ≤2ppm |
| Microbiological Tests | |
| Total Plate Count | ≤300cfu/g |
| Total Yeast & Mold | ≤100cfu/g |
4. Kojic Dipalmitate Manufacturer Process Flow Chart
5. Kojic Dipalmitate Benefits
Skin-whitening
Kojic Acid Dipalmitate can effectively restrain the activity of tyrosinase. It can repair skin problems, including chloasma, age spots, pigmentation, etc. Moreover, it has effect of sun block and skin-lightening. KAD possesses a good skin-whitening function.
6. BFSTAR Kojic Dipalmitate Characteristic
1. Good stability in heat and light; no color change.
2. Good oil solubility.
7. Kojic Acid Dipalmitate Application and Dosage
| Application | Product | Reference Dosage |
| Cosmetics | Mask, essence, cream, moisturizer | 1% -3% |
Kojic Acid Dipalmitate application cases in cosmetics brand around the world:
| Country | Brand | Product | Main ingredient |
| USA | Petal Fresh | Anti-Wrinkle Cream | Aqua (Water), Glycerin, Cetyl Alcohol, Stearyl Alcohol, Stearic Acid, Kojic Dipalmitate, Rubus Idaeus Fruit Extract, Punica Granatum Extract, Persea Gratissima Oil, Aloe Vera Leaf Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract, Rosa Canina Fruit Extract, Vaccinium Myrtillus Fruit/Leaf Extract, Saccharum Officinarum Extract, Citrus Aurantium Dulcis Fruit Extract, Citrus Medica Limonum Fruit Extract, Collagen, Vitamin A, Dehydroacetic Acid, Benzyl Alcohol, Fragrance |
| Palmer’s | Dark Spot Corrector and Fade Serum | Kojic Dipalmitate, Hydroquinone, Retinol, Alpha Hydroxy Fruit Acids, Vitamin C, Vitamin E, Bilberry Extract, Shea Butter | |
| DeVita | Skin Brightening Serum | Aloe Barbadensis, Magnesium Ascorbyl Phosphate, Capric/Caprylic Triglycerides, Olea Europaea Oil, Panthenol, Phyllanthus Emblica Fruit Extract, Kojic Dipalmitate, Arbutin, Persea Gratissima Oil, Centella Asiatica, Tocopherol, Nicotinate, Bearberry Leaf Extract, Citrus Paradisi Seed Extract, Thymus Vulgaris Essential Oil, Potassium Sorbate. |
8. Kojic Acid Dipalmitate Reference Formula
- Anti-freckle and whitening mask:
| Ingredient | Content（%） | Ingredient | Content（%） |
| Kojic Acid Dipalmitate | 0.3 | Silk protein | 3.0 |
| Ethanol | 3.0 | Polyacrylic acid | 1.0 |
| Methylparaben | 0.1 | Propolis | 3.0 |
| Squalane | 2.0 | Propylene glycol | 5.0 |
| Zinc Oxide | 10.0 | Kaolin | 10.0 |
| Fragrance | Appropriate amount | ||
- Whitening toner:
| Ingredient | Content（%） | Ingredient | Content（%） |
| Kojic Acid Dipalmitate | 0.15 | Oleyl alcohol polyglycol ether | 2.0 |
| Fragrance | Appropriate amount | Preservative | Appropriate amount |
| Potassium hydroxide | 0.03 | Polyethylene glycol | 2.0 |
| Placenta fluid | 8.0 | Purified water | Add to 100 |
| Glycerin | 5.0 | Ethanol | 10.0 |
- Anti-aging moisturizing cream：
| Ingredient | Content（%） | Ingredient | Content（%） | ||
| Group A | Atractylodes | 5-10 | Poria Locos | 5-10 | |
| Ampelopsis japonica | 5-10 | Angelica dahurica | 5-10 | ||
| Common bletilla pseudobulb | 5-10 | ||||
| Group B | Glycerin | 3-8 | Camellia Sinensis | 1-3 | |
| Vitamin A | 1-2 | SOD | 0.3-0.7 | ||
| Kojic acid dipalmitate | 0.5-2 | ||||
| Vaseline | 20-40 | Distilled water | 10-15 | ||
| Water | 75-250 | ||||
Preparation method:
Take Group A ingredients, smash and mix them well, then get mixture 1; Pour mixture 1 into water for 1 to 3 hours( ratio is 1：3), filtrate, and boil the filtration again, then filtrate again and get the filtration 2. Concentrate the filtration 2, then get filtration 3; add distilled water into Group B ingredients and heat to obtain mixture 4; heat vaseline until melting, then add filtration 3 and mixture 4, stir well and cool it, then get the cream.
9. Kojic Dipalmitate Safety
On the Announcement of Name List of Cosmetics Raw Material published by China Food and Drug Administration in 2014, and The Catalog Of the International Cosmetics Raw Material Standard English Name issued by CTFA ，EU and CAFFCI in 2010 both have recognized Kojic Acid Dipalmitate as a raw material of cosmetics. There is no reports showing its insecurity for external use. Kojic Acid Dipalmitate has a higher stability than Vitamin-C, so it is efficient and has no side effects.
10. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place away from direct sunlight and oxidizing agents.
