100% Natural Psoralea Corylifolia Extract Bakuchiol for Anti-aging

Bakuchiol is a new, natural cosmetics ingredient for anti-aging and skin irritation relieving. It also is a great alternative for retinol, because it’s more mild than retinol for sensitive skin. Bakuchiol is obtained form the seed of plant psoralea corylifolia. BFSTAR develops high purity Bakuchiol of 98%. Studies have show that Bakuchiol has effect of anti-aging. It can enhance the activity of human skin fibroblasts and promote the synthesis of skin collagen, thus achieving its anti-aging effect. Moreover, it can significantly reduce UV-induced skin damage, such as pigmentation. So Bakuchiol is an effective skin-whitening raw material.

In recent years, there have been more and more researches on Bakuchiol, and its effect on beauty and skin care has also attracted wide attention. Bakuchiol is an active cosmetic ingredient with great potential and multiple effects.

Product Name	CAS Number	INCI Name
Bakuchiol	10309-37-2	BAKUCHIOL
Molecular Formula	Molecular Weight	Molecular Structure
C18H24O	256.38g/mol
Product ID	Specification	Minimal Package	Minimal Order Quantity
BFSTAR150101	98%	1KG	1KG

2. Bakuchiol Source

Psoralea corylifolia, also named babchi, is an annual plant, usually used in Indian and Chinese traditional medicine. It is distributed in China, India, Burma and Sri Lanka. The plant grows on a hillside, by a stream or by a field. Its seeds mainly contain coumarins , including psoralen and isopsoralen. Bakuchiol is extracted from babchi’s seed.

3. Bakuchiol Manufacturer Specifications

Items	Specification
Bakuchiol	≥98%
Psoralen	≤10ppm
Organoleptic Tests
Appearance	Light red-brown to light yellow oil
Odor	Gentle and characteristic odor, not pungent
Heavy Metals
Total heavy metals	≤10.0ppm
Lead	≤2.0ppm
Mercury	≤1.0ppm
Cadmium	≤0.5ppm
Microbiological Tests
Total plate count	≤1000cfu/g
Yeast & mold	≤100cfu/g
E.Coli	Negative
Salmonella	Negative
Staphylococcus aureus	Negative

4. Bakuchiol Benefits

• Anti-aging

The study has been shown that Bakuchiol can enhance fibroblastic activity in skin, increase TIMP-2 , and decrease MMP-1. Thus it can reduce the breakdown of collagen in skin, and promote collagen ’s synthesis, then achieving its anti-aging effect. Also, Bakuchiol is able to promote the proliferation of ESF-1 cells and collagen ’s expression, and to inhibit the expression of matrix metalloproteinase mRNA, so as to play an anti-aging effect on the skin.

After 12 weeks of treatment with bakuchiol, the subjects’ skin wrinkles and pigmentation were significantly improved. There was no any adverse reactions on skin.

• Anti-inflammation

Bakuchiol can inhibit nucleic acid synthesis by degrading DNA helix and topoisomerase II enzyme activity, thereby hindering DNA biosynthesis and eventually leading to bacterial deathis. It is also known to be an effective in reducing acne especially when combined with salicylic acid, which results in a synergistic and effective treatment of acne.

• Skin-Whitening

Bakuchiol mainly affects the activities of tyrosine monophenolase and diphenolase. Studies have found that in the low concentration range, Bakuchiol has a more pronounced inhibitory effect on tyrosinase than arbutin, which has become a potential natural tyrosinase inhibitors.

5. Study on the Pharmacology of Bakuchiol and Cosmetics

Test item	Concentration	Result
Inhibition to tyrosinase activity	/	IC50: 12.1μg/mL
Inhibition to collagen protease activity	/	IC50: 0.1% or so
Inhibition to myeloperoxidase	/	IC50: 0.1μmol/L
Inhibition to prostaglandin PGE2	0.1μmol/L	Inhibition rate: 33.8%
Inhibition to ear swelling in mice	1%	Inhibition rate: 5.74%
Inhibition to pigmentation by SPF method	1%	Inhibition rate: 2.86%

6. BFSTAR Bakuchiol Characteristic

• BFSTAR Bakuchiol has good stability and little side effect.
• BFSTAR Bakuchiol is 100% natural extraction with high purity.
• BFSTAR Bakuchiol’s color, solution color and odour are lighter, and impurities are less than other Bakuchiol on the market.

7. Bakuchiol Application & Reference Dosage

Bakuchiol is widely used in anti-aging, anti-acne and skin-whitening cosmetics, including spray, toner, lotion, essence, face cream, sunscreen, etc.

Application Product	Reference Dosage
Toner, lotion, essence, face cream, sunscreen, etc.	0.5-2%

Note:

• Bakuchiol can be paired with salicylic acid to treat acne, used in skin care product.
  

• Bakuchiol has no photo-sensitivity for skin; it’s more tolerant than Retinol.

Bakuchiol application cases in major cosmetic brands in the world

Country	Brand	Product
China	REN Bio Retinoid	Anti-wrinkle Concentration Oil Anti-aging Cream
America	Kate Somerville	Dermalquench Liquid Lift + Retinol Retinol firming eye cream
	Paula’s Choice	Clinical 0.3% Retinol + 2% Bakuchiol Serum
German	Sepai	Flawless Dark Spots Serum Sublime Youth Oil Flawless Body Secret
France	Noreva	Exfoliac Global 6 Intensive Care
	Bioderma	Sebium global intensive purifying care acne-prone skin

10. Package and Storage

1.Sample bottles are 30ml and 50ml glass bottles.

2.The products in small batches are packed in 1kg, 5kg and 10kgPE bottles.

3.The outer packing of large quantity products is 200L bucket.